Eukaryotic genome organisation pdf

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Views Total views. Actions Shares. No notes for slide. What is Genome? Needed for coding, regulation and replication of DNA. Much more in no than functional sequences. Genome of all living organisms represents their hereditary material and is formed of DNA.

In Prokaryotic cellsGenomic DNA forms a single circular chromosome, without basic proteins , lies in the cell cytoplasm in nucleoid region In Eukaryotic cellsDNA is associated with basic proteins histones , form long chromatin fibers. Chromatin fibers form a network, enclosed in a double layered nuclear envelop, condenses into chromosomes during cell division 5. It is an organelle submerged in its sea of turbulent cytoplasm which has the genetic information encoding the past history and future prospects of the cell.

Nucleosome with histone H1 Histone Octamer a nucleosome It is late replicating during the s-phase of the cell and is not transcribed. DNA, being the only permanent component of chromatin, is the sole genetic material of eukaryotes. So the chromatin contains genetic material instructions to direct cell function.

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